Y. M. Kassim, V. B. S. Prasath, O. Glinskii, V. Glinsky, V. Huxley, and K. Palaniappan

Proc. IEEE Applied Imagery Pattern Recognition (AIPR), 2016

random forest, segmentation, vasculature, confocal, biomedical

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Abstract

In this paper, we consider confocal microscopy based vessel segmentation with optimized features and random forest classification. By utilizing vessel-specific features tuned to capture curvilinear structures such as multiscale Frobenius norm of the Hessian eigenvalues, Laplacian of Gaussians we obtain better segmentation results in challenging imaging conditions. We obtain binary segmentations using random forest classifier trained on physiologists marked ground-truth. Experimental results on mice dura mater confocal microscopy vessel segmentations indicate that we obtain better results compared to global segmentation approaches.